This fight against our own body's processes reminds me of a battle I had with the thermostat in our old apartment. It was a fancy thing, designed to keep temperature constant between a range of high and low temperatures. It had a flaw however. If temperatures snuck above the high setting, the furnace would blow full blast until it got cooler. Think about that for a minute. Our solution? If it were a cool day, we would open every window in the house in the hopes of beating the furnace. If it was a hot day, we would have to set the thermostat above the ambient temperature. Over the next few days, I would gradually lower the higher setting on the thermostat, as the apartment cooled. It was a trick to fix a flaw.
I have also been thinking of the complex interplay of hormones that regulate hunger and weight. The miracle of insulin was solved when the discoverers realized it has a balanced relationship with glucose. Neither can be too high.
|Nicholas Perony's Bats|
|Representation of Penfield's Brain Map|
So again, back to the disentangling. Perhaps this could be mapped out using the new technology that allows us to build analogues of bodily systems; organs on a chip.
If we build a successful analogue that replicates the body's propensity to obesity (at least among a percentage of the population or under certain conditions), we can then more readily test adding or subtracting the various hormones/foods/interplays.
Perhaps the answer will be to add a new artificial organ/hormone, to create a "too high" setting on our thermostat. A trick to fix a flaw in our makeup.